BRCA1 and triple-negative breast carcinoma: Of participants who satisfied only one of the NDOH criteria (either family history, triple negative breast cancer (TNBC), young age of cancer diagnosis or > 1 primary BC), 11.7% (31/265) had a P/LP variant in BRCA1/2 and 5.1% (12/235) in one of the other BC susceptibility genes.