Similar to AOM-induced liver failure, BDL-induced liver dysfunction was evidenced by increased blood ammonia and plasma ALT and alkaline phosphatase levels, but these changes were alleviated by Tyr or YQ treatment (Fig. 6k, l, m, p, q, and r; k, F(3,42) = 8.448, P < 0.001; l, F(3,47) = 37.74, P < 0.001; m, F(3,43) = 64.22, P < 0.001; p, F(3,17) = 5.806, P = 0.006; q, F(3,20) = 21.93, P < 0.001; r, F(3,16) = 9.749, P < 0.001). This evidence concerns the gene GPT and liver failure.