A recent systematic review and meta-analysis found that IFN-γ, TNF, IL-2, IL-6, IL-8, IL-18, IL-22, chemerin, lipocalin-2, resistin, sE-selectin, fibrinogen, and C3 were elevated in patients with psoriasis compared to healthy controls, while IL-1β, IL-4, IL10, IL-12, IL-17, IL-21, IL-23, visfatin, and omentin were not significantly different in patients with psoriasis compared to controls [16]. This evidence concerns the gene LCN2 and psoriasis.