GPT and obesity due to melanocortin 4 receptor deficiency: Among these, 1 study from the nationwide multiethnic Million Veterans Program evaluated a surrogate measure of hepatic steatosis defined by chronic ALT elevation,67 while another study meta-analyzed imaging-based cohort studies (Genetics of Obesity-related Liver Disease consortium and UK Biobank MRI-PDFF) with diagnosis code-based steatosis cohorts (UK Biobank, FinnGen, and electronic MEdical Record and GEnomics [eMERGE]).