Gene set enrichment analysis (GSEA) highlighted some similar pathways differentiating uninfected and infected macaques (Supplemental Figure 1; supplemental material available online with this article; https://doi.org/10.1172/jci.insight.186003DS1), but only platelet activation and TNF-α pathways had some statistical support, possibly due to extensive heterogeneity in individual macaque responses to infection. Here, TNF is linked to infection.