The expression of LMNB2 was positively related with TMB in LGG, BRCA, LUAD, STAD, UCEC, ACC, PRAD, SARC, SKCM, rectum adenocarcinoma (READ), PAAD, BLCA, uterine carcinosarcoma (UCS), kidney chromophobe (KICH), cholangiocarcinoma (CHOL), LUSC and MESO, but negatively related with TMB in THYM (Supplementary Figure 3A). The gene discussed is LMNB2; the disease is bladder transitional cell carcinoma.