They included well-known candidates in cancer such as ALDOC, HIF1A (in glycolysis), SNAI2, ZEB1 (in epithelial-mesenchymal transition), monocarboxylate transport 4 (SLC16A3), MMP2, GPNMB, KRT17, and INHBA (all of which were upregulated), as well as downregulated genes such as GATA4, ADH1A, PTF1A, CBS, and genes encoding pancreatic digestive enzymes (e.g., PRSS1, CPA1, and CPB1). This evidence concerns the gene HIF1A and cancer.