CARINH and infection: Visualization of the distribution of infection foci in the lungs of Carinh−/− mice by immunostaining of the IAV nucleocapsid (Fig 7E, green area) and measurement of whole lung viral Pr8 RNA content at day 4 post-infection revealed a 2.5-fold higher viral burden in Carinh−/− compared with WT mice (Fig 7F).