CARINH has been shown to be induced by IFN in esophageal squamous cell carcinoma and HeLa cells (Huang et al, 2019; Barriocanal et al, 2022), and deletion of its promoter region leads to decreased cell survival upon infection with encephalomyocarditis virus (Barriocanal et al, 2022). The gene discussed is CARINH; the disease is infection.