lncRNA Colitis Associated IRF1 antisense Regulator of INtestinal Homeostasis (CARINH) (Ma et al, 2023), also known as C5ORF56 (Chiaroni-Clarke et al, 2014) and ISR8/IRF1-AS1 (Barriocanal et al, 2022), is located on the opposite strand of the interferon regulatory factor 1 (IRF1) gene, in the antisense direction. The gene discussed is IRF1; the disease is colitis.