Nestin-Fgf13 cKO male mice suffered spontaneous seizures in their home cage (Video 1) as early as P12, followed by premature death (Figure 1D), consistent with mouse models of DEE that exhibit SUDEP (Bunton-Stasyshyn et al., 2019; Han et al., 2020). The gene discussed is FGF13; the disease is developmental and epileptic encephalopathy.