To investigate the crude component activates NOD1/NF-κB pathway and enhances the CCL5-secreting phenotype of tumor cells, we then collected the conditional medium of L. intestinalis (L. int-CM) and subsequently lysis the bacteria pellet with ultrasonic followed by centrifugation to preliminary separation the bacterial fractions as supernatant and precipitation (Figure S6e). The gene discussed is NFKB1; the disease is neoplasm.