Although the precise mechanisms underlying the CCL5 network need further elucidation, and studies focusing on the inhibitory effects of CCL5 secreted from tumor cells on tumorigenesis remain limited, researchers have been dedicated to investigating CCL5 as a modulator in the tumor microenvironment.50–53 This approach has exhibited considerable potential in enhancing immune infiltration and mitigating tumor burdens. This evidence concerns the gene CCL5 and neoplasm.