The Veterans Health Administration (VA) generated a first prediction tool that included twelve routinely available variables (treatment response, age, gender, body mass index, ethnicity, HCV genotype, platelet count, AST, ALT, albumin, international normalized ratio, and hemoglobin) to estimate the 3-year HCC risk after antiviral treatment through a multivariable Cox proportional hazards model, in patients both with and without cirrhosis [240]. Here, ALB is linked to hepatocellular carcinoma.