The up-regulation of TRIM44 can be detected in various kinds of cancer, such as osteosarcoma, gastric cancer, lung cancer, breast cancer, papillary thyroid cancer, testicular germ cell tumor, gastric cancer, and prostate cancer, which suggested that TRIM44 presented a broad spectrum of expression in tissues [29,30]. Here, TRIM44 is linked to thyroid gland papillary carcinoma.