Cheeti et al. (2013) [9] studied demographic and laboratory variables (e.g., albumin or AAG serum levels) in a cohort of patients with cancer; they modeled equations based on observed data to predict a virtual oncology population that was subsequently integrated into the whole-body PBPK software SimcypTM (Certara USA and Certara UK Ltd. “Simcyp”). Here, ALB is linked to cancer.