EGFR and glioblastoma: Figure 9A shows that the AUC values of PER3, BEAF, and EGFR are all above 0.9. Additionally, the AUC values of PER3 for predicting the survival rate of GBM patients at both 5 and 7 years are greater than 0.7. These data further suggest that PER3 is a potential diagnostic and prognostic biomarker for GBM [45].