The researchers also found higher levels of Staphylococcus epidermidis and S. aureus colonization in the nasal mucus of patients with allergic rhinitis compared to the healthy population, and further experiments revealed that S. aureus inhibited the production of IL-33 by epithelial cells and reduced Th2 cell-mediated allergic rhinitis [48]. The gene discussed is IL33; the disease is allergic rhinitis.