CCL5 and infection: It has been shown that infections with HRV, RSV, or hPIVs result in significant pyroptosis-related respiratory epithelium damage, characterized by an increased secretion of pro-inflammatory molecules, including cytokines (IL-1, TNF-α, GM-CSF, IL-6, IL-11) and chemokines (RANTES, IL-8, MIP-1α) [55,56,57].