In the study by Aggarwal et al. high number of PSMA-positive lesions, high baseline PSMA-derived Tumor Volume (PSMA-TV) and Total Lesion PSMA (TL-PSMA) were all significantly correlated with OS of ccRCC patients with HR 6.7, 8.9, 8.9 [60]. This evidence concerns the gene FOLH1 and neoplasm.