In the study by Tariq et al., in which each RCC patient (91% ccRCC) underwent both [18F]FDG PET/CT and PSMA PET/CT for primary tumor evaluation, uptake of both tracers was seen in 40%, PSMA uptake alone in 20%, and [18F]FDG uptake alone in 40% of lesions. The gene discussed is FOLH1; the disease is renal cell carcinoma.