AKT1 and Hepatic fibrosis: The results showed that salidroside inhibited CXCL16-induced cell migration and a high expression of Col I and α-SMA mRNA, and the phosphorylation of Akt, indicating that salidroside can attenuate hepatic fibrosis, and the mechanism may be related to the inhibition of CXCL16-induced migration and Akt phosphorylation [159].