WNT3A and renal fibrosis: In addition, Shati et al. [162] found that salidroside could significantly reduce the total levels of Wnt1, Wnt3, and β-catenin in rats with renal fibrosis, suggesting that salidroside may play an anti-renal fibrosis role by inhibiting the Wnt1/Wnt3a/β-catenin signaling pathway.