MTOR and colorectal cancer: In an experimental study on human colorectal cancer cells (HT-29 cells), salidroside (0.5, 1, and 2 mM incubation for 48 h) dose-dependently decreased the expression rate of Bcl-2/Bax and inhibited the phosphorylation of PI3K, Akt, and mTOR, suggesting that salidroside induced apoptosis of human colorectal cancer cells by inhibiting the PI3K/Akt/mTOR pathway [165,166,167].