Using cecum ligation and puncture to replicate the sepsis mice model, it was found that salidroside (80, 160, and 320 mg/kg intraperitoneally) could down-regulate the expression of NF-κB p65 and p38 MAPK, suggesting that salidroside has a protective effect on intestinal barrier dysfunction by inhibiting the NF-κB/p38 MAPK signaling pathway [151]. Here, NFKB1 is linked to Sepsis.