Cancers in which TRPA1 is significantly underexpressed, and therefore may act as a tumor suppressor, are bladder urothelial carcinoma (BLCA), colon adenocarcinoma (COAD), kidney chromophobe (KICH), glioblastoma multiforme (GBM) and rectum adenocarcinoma (READ). This evidence concerns the gene TRPA1 and neoplasm.