TP53 and breast carcinoma: In a concluding remark, the anti-proliferative and anti-tumor potential of synthesized azomethine scaffold, BCS3, was elucidated against in vitro and in vivo breast cancer cells by antagonizing IAPs to regulate MDM2-p53 and Bcl-2-caspase axes that potentiated intrinsic and extrinsic apoptotic pathways after the determination of its promising binding affinity with the BIR3 domain of IAPs through in silico molecular docking studies.