Anti-NMDAR Aabs of the IgG class directed against the GluN1 (NR1) subunit have been found in the CSF of patients with anti-NMDAR encephalitis (ANRE), a condition characterised by seizures, psychosis and cognitive deficits [3], and in patients with forms of autoimmune epilepsy [4,5]. This evidence concerns the gene GRIN1 and viral encephalitis.