AKT1 and cancer: KEGG pathway analysis revealed nine pathways related to the DEGs (Tabel S4), including extracellular matrix (ECM)-receptor interaction, peroxisome proliferator-activated receptor (PPAR), leukocyte transendothelial migration, regulation of lipolysis in adipocytes, cytoskeleton organization in muscle cells, focal adhesion, proteoglycans in cancer, the PI3K-Akt signaling pathway, and malaria signaling pathways (Figure 1G).