On day 14, while c6-rTMS (n = 5) animals exhibited increased T2w-hyper-intensity compared to day 7 [24.77% (18.57–45.12), p = 0.047, Mann–Whitney), the T2w signal in c6-rTMS-IGFT rats (n = 4) did not significantly increase relative to day 7 [30.84% (14.65–32.14), day 14 vs. day 7—p = 0.089, Mann–Whitney] (Figure 2C, top), suggesting that rTMS-coupled IGF-Trap could slow tumor progression. Here, IGF1 is linked to neoplasm.