IRF1 and eosinophilic granulomatosis with polyangiitis: TSLP, IRF1/IL5, GATA3, LPP/BCL6, CDK6, BIM and BACH2 encode proteins involved in TH2 responses and eosinophilic inflammation, both key in EGPA, and many of these genes have also been implicated in asthma [59].