Consistently high expression of MITF and other key genes involved in melanogenesis, like the tyrosinase-related protein 1 (TYRP1), CDK2 and human homologue of murine silver (SILV/PMEL17/GP100), in EWSR1::ATF1 fusion-positive soft-tissue clear cell sarcomas further suggests that genes of melanin metabolism are bona fide targets of EWSR1::ATF1 chimeras, at least, in CCS. This evidence concerns the gene ATF1 and clear cell sarcoma.