In GTL16 gastric carcinoma cells, Franco et al. (2010) [40] found that CD151 associates with the MET receptor, driving β4 integrin phosphorylation and facilitating the coupling of MET with Gab1–Grb2 (growth factor receptor-bound protein 2) to promote MAPK phosphorylation and tumor growth. The gene discussed is GRB2; the disease is neoplasm.