In glioblastoma multiforme (GBM), the vascular endothelial growth factor (VEGF) suppresses tumor cell invasion by promoting the recruitment of protein tyrosine phosphatase 1B (PTP1B) to a complex formed by MET and VEGF receptor 2 (VEGFR2, Figure 2) [30]. The gene discussed is PTPN1; the disease is glioblastoma.