In addition, Jia et al. [59] have shown that newly diagnosed AML patients exhibited higher expression of NLRP3 inflammasome and aryl hydrocarbon receptor (AHR) in the bone marrow and peripheral blood, along with elevated IL-18 levels and an increased Th22/Th1 ratio compared to patients in complete remission and normal controls. Here, NLRP3 is linked to acute myeloid leukemia.