These were the two well-known biomarkers of HF, MI, and heart stress NT-proBNP/BNP-32 [49] and troponin T [50], as well as promising markers angiopoietin-2 [51] and thrombospondin-2 [52], and the newly outlined latent transforming growth factor beta binding protein 4 and follistatin-related protein 3 [53]. The gene discussed is LTBP4; the disease is hydrops fetalis.