However, we observed several nominally significant associations: In the overall sample, NKG2C+ B cells tended to be increased in individuals at higher genetic PD risk (variance explained [∆R2] = 1.5%, p = 0.026) with consistent effect directions across subgroups and the strongest effect observed in women (∆R2 = 2.9%, p = 0.014, Table 1). This evidence concerns the gene KLRC2 and Parkinson disease.