The validation by qRT-PCR of these data showed the increased expression of different lncRNAs, such as RP4-754E20_A.5, XLOC_01234, XLOC_000283, LINC02618, LINC02828, LINC01926, LINC01094, LINC02705, LINC00278, LINC01724, LINC01857, ANKRD44-IT1, IL10RB-DT, LINC02148, LINC02123 and LINC01665, as well as the reduced expression of LINC00475, ADAMTS9-AS2 and LINC00290 in samples with pulpitis compared with control samples of healthy pulp [34,36,37,42]; however, the biological functions of these lncRNAs in pulpitis or the involved molecular mechanisms were not explored experimentally. The gene discussed is IL10RB; the disease is pulpitis.