Among 220 MM-specific genes, IGF1 [16], SLAMF7 [21], ITGA8 [22], IL5RA [23], TJPI [24], GPRC5D [25], DKK1 [26], and WNT5A [27] harbor known significance for MM, whereas most others have weaker connections to the disease. The gene discussed is GPRC5D; the disease is Miyoshi myopathy.