The percentage of Tc lymphocytes (CD3+CD4-CD8+) was higher in the CRC rats compared to the controls (A vs. C) (ANOVA, p < 0.02), with the highest value found in the A0 group fed the diet without OBG compared to the groups fed the diet with this additive, regardless of its level (A1 and A3) (p < 0.05). Here, CD8A is linked to colorectal carcinoma.