For instance, collagen regulates the extension of invadopodia through the integrin αvβ3/Dishevelled-associated activator of morphogenesis 1 (DAAM1)/Ras Homolog family member A (RHOA)-dependent cascade [66], which are small actin-rich protrusions that mediate the invasion of tumor cells [67]. The gene discussed is DAAM1; the disease is neoplasm.