Since we did not observe any signs of retinal degeneration in the myopic marmosets, the reduction in retinal nerve fiber layer thickness, ganglion cell and astrocyte density, increase in the expression and intensity of GFAP expression may be very early markers present prior to the development of myopia-related pathologies such as glaucoma, retinal detachment and myopic maculopathy. This evidence concerns the gene GFAP and retinal degeneration.