However, other studies [19,33] found a statistically significant increased risk of POAG associated with the MMP1 rs1799757 2G/2G genotype and -1607 2G allele as well as for the MMP9 rs3918249 (genotype C/T) and the -1562 T allele in Polish patients with POAG compared to healthy controls [19]. The gene discussed is MMP9; the disease is open-angle glaucoma.