RPN2 and mucopolysaccharidosis: Other genes that exhibited altered expression levels compared to control cells in five neuronopathic MPS types/subtypes included down-regulated C11orf58 (corresponding to Chromosome 11 Open Reading Frame 58) and MINOS1 (coding for Myosin X), and up-regulated RPN2 (coding for Ribophorin II), PDIA3 (coding for Protein Disulfide Isomerase Family A Member 3), and VASN (coding for Vasorin).