CEBPA and metabolic dysfunction-associated steatotic liver disease: In response to sustained overfeeding, preadipocytes differentiate into mature adipocytes, driven by transcription factors, such as proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer-binding protein alpha (C/EBPα), increasing fat storage capacity and mitigating metabolic risks associated with ectopic fat deposition in organs like the liver (non-alcoholic fatty liver disease) and muscle (myosteatosis) [43].