Furthermore, we identified two distinct patterns of OR expression in malignant cells: OR7D2 showed uniformly elevated expression across all malignant cellular states compared to non-neoplastic cells, suggesting its fundamental role in GBM progression, while OR4N2 and OR7E14P exhibited state-dependent expression patterns, indicating their involvement in regulating GBM cellular plasticity. Here, OR7D2 is linked to glioblastoma.