THBS2 and central nervous system cancer: Additionally, miR-126 boosts the pro-angiogenic effects of VEGF and FGF, while miR-9 promotes angiogenesis in glioma cells by targeting thrombospondin 2 (THBS-2), patched homolog 1 (PTCH1), and prolyl hydroxylase 3 (PHD3) [66].