SLC7A11 and pancreatic neoplasm: As an interesting finding in a genetically engineered mouse (KrasFSF.G12D/+; Tp53R172H/+; Pdx1FlpOtg/+; Slc7a11Fl/Fl; Rosa26CreERT2/+, termed KPFSR mice) model, in which the administration of tamoxifen induces systemic deletion of Slc7a11, KPFSR mice receiving tamoxifen exhibited the induction of tumor-selective ferroptosis and inhibition of pancreatic cancer growth, and the administration of cyst(e)inase can replicate the result in KPC mice [87].