An 11-gene signature (Hmga2, Peak 1, Kras, Slc2a1, Ankfn1, Ahnak, Cmss1, Fmo5, Gphn, Plec, Gstt2) had the most substantial impact on disease-free survival in bladder cancer patients (Supplementary Table S5, Figure 5C–E). This evidence concerns the gene PLEC and urinary bladder carcinoma.