In addition, ALL-MSCs’ secretome lacked proteins essential for endothelial proliferation, the regulation of platelet activation, response to vitamin D, the chemotaxis and migration of blood cells, the regulation of growth and other vital functions: CCL5, CTSB, CTSC, CTSF, CXCL1, CXCL8, EGFR, FABP5, ICAM1, FGFR1, FTL, HGF, HLA-DQ, IGF2, IGF2R, MET, SERPINA3, LTBP4, PDGFRB, SF3B1, SPP1, TGFB1, TGFB2 and YAP1. The gene discussed is ICAM1; the disease is acute lymphoblastic leukemia.