In addition, ALL-MSCs’ secretome lacked proteins essential for endothelial proliferation, the regulation of platelet activation, response to vitamin D, the chemotaxis and migration of blood cells, the regulation of growth and other vital functions: CCL5, CTSB, CTSC, CTSF, CXCL1, CXCL8, EGFR, FABP5, ICAM1, FGFR1, FTL, HGF, HLA-DQ, IGF2, IGF2R, MET, SERPINA3, LTBP4, PDGFRB, SF3B1, SPP1, TGFB1, TGFB2 and YAP1. This evidence concerns the gene SERPINA3 and acute lymphoblastic leukemia.