There was no significant difference observed in the age, body mass index (BMI), duration of diabetes, blood glucose, HbA1c, creatinine, uric acid, hsCRP, VCAM-1, ICAM-1, or oxLDL levels, or lipid parameters between the patient groups both in response to ALA treatment and when compared to the controls. The gene discussed is ICAM1; the disease is diabetes mellitus.