ALK and anaplastic large cell lymphoma: In a prior study from our group [14], it was reported that miR-122-5p levels in circulating sEVs at the DIA were elevated in pediatric anaplastic lymphoma kinase-positive (ALK+) anaplastic large cell lymphoma (ALCL) as compared to healthy donors (HDs) and that this miRNA was barely detectable in ALK+ ALCL-involved lymph nodes, in reactive lymph nodes, and extranodal skin biopsies.