Examples of Nrf2 activators are sulforaphane (from cruciferous vegetables), which protects against lung and pancreatic cancers [71]; oltipraz, a synthetic compound that inhibits cancer formation in rodent models and may mitigate non-alcoholic steatohepatitis [72,73]; and dimethyl fumarate (DMF), FDA-approved for multiple sclerosis, with potential tumor-preventive effects [74]. Here, NFE2L2 is linked to multiple sclerosis.