A novel PD-L1 tracer, developed by Radaram et al., [89Zr]Zr-p-SCN-Bn-C5HOPO-STM108, was tested in PD-L1-positive TNBC xenografts and showed superior tumor contrast compared to [89Zr]Zr-DFO-STM108. The gene discussed is CD274; the disease is neoplasm.