A study by Rosestedt et al. using [68Ga]Ga-HEHEHE-ZHER3:8698-NOTA in preclinical models with various cancers, including breast cancer, demonstrated the tracer’s high specificity for HER3, showing a significant correlation (r = 0.66) between tumor uptake and HER3 expression. Here, ERBB3 is linked to breast carcinoma.