In this real-word data analysis, we aimed to investigate the effects of SGLT-2 inhibitors on body composition and fluid status in patients with CAD and HF participating in a CR program, specifically analyzing their impacts on the BFM, LBM, and TBW (intracellular water (ICW) and extracellular water (ECW)) distribution measured by BIA. The gene discussed is SLC5A2; the disease is coronary artery disorder.