In the control group, a total of 246 samples from healthy individuals without pAD diagnosis were analyzed, with the ApoE genotypic order being ε3/ε3 > ε3/ε4 > ε2/ε3 > ε2/ε4 > ε2/ε2 and without finding, in this case, homozygous carriers of the ε4 allele (ε4/ε4). Here, APOE is linked to peripheral arterial disease.