Several preclinical studies have demonstrated the potential role of DSCC1 in cancer progression in many cancers, including gastric cancer [21], lung adenocarcinoma [8], and BC [11]; however, this is the first study to conduct a comprehensive analysis of the correlation between DSCC1 and clinicopathological parameters and patient outcomes at the transcriptomic and protein levels. Here, DSCC1 is linked to lung adenocarcinoma.