NPPB and pulmonary arterial hypertension: To assess the predictive performance of the nomogram, the ROC curves were plotted for the clinical model (including PAH subtype, 6MWD, and WHO-FC) and the nomogram model for the prediction of clinical worsening events, as well as the 2022 ESC/ERS model (including BNP, 6MWD, and WHO-FC) and the ESC model plus the LCR (Figure 5).